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Ly49C-Dependent Control of MCMV Infection by NK Cells Is Cis-Regulated by MHC Class I Molecules

Natural Killer (NK) cells are crucial in early resistance to murine cytomegalovirus (MCMV) infection. In B6 mice, the activating Ly49H receptor recognizes the viral m157 glycoprotein on infected cells. We previously identified a mutant strain (MCMV(G1F)) whose variant m157 also binds the inhibitory...

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Bibliografski detalji
Glavni autori: Forbes, Catherine A., Scalzo, Anthony A., Degli-Esposti, Mariapia A., Coudert, Jerome D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038614/
https://ncbi.nlm.nih.gov/pubmed/24873973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004161
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