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Contrasting effects of anti-Ly49A due to MHC class I cis-binding on NK cell mediated allogeneic bone marrow cell resistance
NK subsets have activating and inhibitory receptors that bind MHC-I. Ly49A is a mouse inhibitory receptor that binds with high affinity to H2(d) in both a cis- and trans-manner. Ly49A cis-associations limit trans-interactions with H2(d)-expressing targets as well as monoclonal antibody (mAb)-binding...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733663/ https://ncbi.nlm.nih.gov/pubmed/23752612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300202 |
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