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Effects of MHC Class I Alleles on Licensing of Ly49A(+) NK Cells

Natural killer (NK) cells are innate immune lymphocytes that can react to cells lacking self-MHC class I. However, NK cells that cannot engage self-MHC through an inhibitory receptor are resistant to stimulation through their activation receptors. To become licensed, i.e. functionally competent to b...

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Detalhes bibliográficos
Main Authors: Jonsson, A. Helena, Yang, Liping, Kim, Sungjin, Taffner, Samantha M., Yokoyama, Wayne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862662/
https://ncbi.nlm.nih.gov/pubmed/20194719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904057
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