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Natural killer cell licensing in mice with inducible expression of MHC class I

Mouse natural killer (NK) cells acquire effector function by an education process termed “licensing” mediated by inhibitory Ly49 receptors which recognize self-MHC class I. Ly49 receptors can bind to MHC class I on targets (in trans) and also to MHC class I on the NK-cell surface (in cis). Which of...

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Detalhes bibliográficos
Main Authors: Ebihara, Takashi, Jonsson, A. Helena, Yokoyama, Wayne M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831452/
https://ncbi.nlm.nih.gov/pubmed/24145414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318255110
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