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Lung parenchyma-derived IL-6 promotes IL-17A–dependent acute lung injury after allogeneic stem cell transplantation

Idiopathic pneumonia syndrome (IPS) is a relatively common, frequently fatal clinical entity, characterized by noninfectious acute lung inflammation following allogeneic stem cell transplantation (SCT), the mechanisms of which are unclear. In this study, we demonstrate that immune suppression with c...

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Pubblicato in:Blood
Autori principali: Varelias, Antiopi, Gartlan, Kate H., Kreijveld, Ellen, Olver, Stuart D., Lor, Mary, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Raffelt, Neil C., Cheong, Melody, Alexander, Kylie A., Koyama, Motoko, Markey, Kate A., Sturgeon, Elise, Leach, Justine, Reddy, Pavan, Kennedy, Glen A., Yanik, Gregory A., Blazar, Bruce R., Tey, Siok-Keen, Clouston, Andrew D., MacDonald, Kelli P. A., Cooke, Kenneth R., Hill, Geoffrey R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457133/
https://ncbi.nlm.nih.gov/pubmed/25673640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-590232
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