PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

BACKGROUND: Chronic airway inflammation in conditions such as cystic fibrosis (CF) and non-CF bronchiectasis is characterised by a predominant neutrophilic inflammatory response, commonly due to the presence of pathogenic bacteria such as Pseudomonas aeruginosa. We hypothesised that down-regulation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Burr, Lucy D., Rogers, Geraint B., Chen, Alice C-H, Taylor, Steven L., Bowler, Simon D., Keating, Rebecca L., Martin, Megan L., Hasnain, Sumaira Z., McGuckin, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095532/
https://ncbi.nlm.nih.gov/pubmed/30114278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202296
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