The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds

av Báez-Santos, Yahira M., St. John, Sarah E., Mesecar, Andrew D.
I publikationen Antiviral Res (2015)

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

av Ratia, Kiira, Kilianski, Andrew, Baez-Santos, Yahira M., Baker, Susan C., Mesecar, Andrew
Publicerad 2014

Catalytic Function and Substrate Specificity of the Papain-Like Protease Domain of nsp3 from the Middle East Respiratory Syndrome Coronavirus

av Báez-Santos, Yahira M., Mielech, Anna M., Deng, Xufang, Baker, Susan, Mesecar, Andrew D.
I publikationen J Virol (2014)

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

av Mielech, Anna M., Kilianski, Andy, Baez-Santos, Yahira M., Mesecar, Andrew D., Baker, Susan C.
Publicerad 2014

X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design

av Clasman, Jozlyn R., Báez-Santos, Yahira M., Mettelman, Robert C., O’Brien, Amornrat, Baker, Susan C., Mesecar, Andrew D.
I publikationen Sci Rep (2017)

X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

av Báez-Santos, Yahira M., Barraza, Scott J., Wilson, Michael W., Agius, Michael P., Mielech, Anna M., Davis, Nicole M., Baker, Susan C., Larsen, Scott D., Mesecar, Andrew D.
Publicerad 2014

Deubiquitinating and Interferon Antagonism Activities of Coronavirus Papain-Like Proteases

av Clementz, Mark A., Chen, Zhongbin, Banach, Bridget S., Wang, Yanhua, Sun, Li, Ratia, Kiira, Baez-Santos, Yahira M., Wang, Jie, Takayama, Jun, Ghosh, Arun K., Li, Kui, Mesecar, Andrew D., Baker, Susan C.
Publicerad 2010

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of...

av Turlington, Mark, Chun, Aspen, Tomar, Sakshi, Eggler, Aimee, Grum-Tokars, Valerie, Jacobs, Jon, Daniels, J. Scott, Dawson, Eric, Saldanha, Adrian, Chase, Peter, Baez-Santos, Yahira M., Lindsley, Craig W., Hodder, Peter, Mesecar, Andrew D., Stauffer, Shaun R.
Publicerad 2013

Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent non-covalent small molecule inhib...

av Jacobs, Jon, Tokars, Valerie, Zhou, Ya, Turlington, Mark, Saldanha, S. Adrian, Chase, Peter, Eggler, Aimee, Dawson, Eric S., Baez-Santos, Yahira M., Tomar, Sakshi, Mielech, Anna M., Baker, Susan C., Lindsley, Craig W., Hodder, Peter, Mesecar, Andrew, Stauffer, Shaun R.
Publicerad 2013