The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds

di Báez-Santos, Yahira M., St. John, Sarah E., Mesecar, Andrew D.
Pubblicato in Antiviral Res (2015)

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

di Ratia, Kiira, Kilianski, Andrew, Baez-Santos, Yahira M., Baker, Susan C., Mesecar, Andrew
Pubblicazione 2014

Catalytic Function and Substrate Specificity of the Papain-Like Protease Domain of nsp3 from the Middle East Respiratory Syndrome Coronavirus

di Báez-Santos, Yahira M., Mielech, Anna M., Deng, Xufang, Baker, Susan, Mesecar, Andrew D.
Pubblicato in J Virol (2014)

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

di Mielech, Anna M., Kilianski, Andy, Baez-Santos, Yahira M., Mesecar, Andrew D., Baker, Susan C.
Pubblicazione 2014

X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design

di Clasman, Jozlyn R., Báez-Santos, Yahira M., Mettelman, Robert C., O’Brien, Amornrat, Baker, Susan C., Mesecar, Andrew D.
Pubblicato in Sci Rep (2017)

X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

di Báez-Santos, Yahira M., Barraza, Scott J., Wilson, Michael W., Agius, Michael P., Mielech, Anna M., Davis, Nicole M., Baker, Susan C., Larsen, Scott D., Mesecar, Andrew D.
Pubblicazione 2014

Deubiquitinating and Interferon Antagonism Activities of Coronavirus Papain-Like Proteases

di Clementz, Mark A., Chen, Zhongbin, Banach, Bridget S., Wang, Yanhua, Sun, Li, Ratia, Kiira, Baez-Santos, Yahira M., Wang, Jie, Takayama, Jun, Ghosh, Arun K., Li, Kui, Mesecar, Andrew D., Baker, Susan C.
Pubblicazione 2010

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of...

di Turlington, Mark, Chun, Aspen, Tomar, Sakshi, Eggler, Aimee, Grum-Tokars, Valerie, Jacobs, Jon, Daniels, J. Scott, Dawson, Eric, Saldanha, Adrian, Chase, Peter, Baez-Santos, Yahira M., Lindsley, Craig W., Hodder, Peter, Mesecar, Andrew D., Stauffer, Shaun R.
Pubblicazione 2013

Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent non-covalent small molecule inhib...

di Jacobs, Jon, Tokars, Valerie, Zhou, Ya, Turlington, Mark, Saldanha, S. Adrian, Chase, Peter, Eggler, Aimee, Dawson, Eric S., Baez-Santos, Yahira M., Tomar, Sakshi, Mielech, Anna M., Baker, Susan C., Lindsley, Craig W., Hodder, Peter, Mesecar, Andrew, Stauffer, Shaun R.
Pubblicazione 2013