The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds

von Báez-Santos, Yahira M., St. John, Sarah E., Mesecar, Andrew D.
Veröffentlicht in Antiviral Res (2015)

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

von Ratia, Kiira, Kilianski, Andrew, Baez-Santos, Yahira M., Baker, Susan C., Mesecar, Andrew
Veröffentlicht 2014

Catalytic Function and Substrate Specificity of the Papain-Like Protease Domain of nsp3 from the Middle East Respiratory Syndrome Coronavirus

von Báez-Santos, Yahira M., Mielech, Anna M., Deng, Xufang, Baker, Susan, Mesecar, Andrew D.
Veröffentlicht in J Virol (2014)

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

von Mielech, Anna M., Kilianski, Andy, Baez-Santos, Yahira M., Mesecar, Andrew D., Baker, Susan C.
Veröffentlicht 2014

X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design

von Clasman, Jozlyn R., Báez-Santos, Yahira M., Mettelman, Robert C., O’Brien, Amornrat, Baker, Susan C., Mesecar, Andrew D.
Veröffentlicht in Sci Rep (2017)

X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

von Báez-Santos, Yahira M., Barraza, Scott J., Wilson, Michael W., Agius, Michael P., Mielech, Anna M., Davis, Nicole M., Baker, Susan C., Larsen, Scott D., Mesecar, Andrew D.
Veröffentlicht 2014

Deubiquitinating and Interferon Antagonism Activities of Coronavirus Papain-Like Proteases

von Clementz, Mark A., Chen, Zhongbin, Banach, Bridget S., Wang, Yanhua, Sun, Li, Ratia, Kiira, Baez-Santos, Yahira M., Wang, Jie, Takayama, Jun, Ghosh, Arun K., Li, Kui, Mesecar, Andrew D., Baker, Susan C.
Veröffentlicht 2010

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of...

von Turlington, Mark, Chun, Aspen, Tomar, Sakshi, Eggler, Aimee, Grum-Tokars, Valerie, Jacobs, Jon, Daniels, J. Scott, Dawson, Eric, Saldanha, Adrian, Chase, Peter, Baez-Santos, Yahira M., Lindsley, Craig W., Hodder, Peter, Mesecar, Andrew D., Stauffer, Shaun R.
Veröffentlicht 2013

Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent non-covalent small molecule inhib...

von Jacobs, Jon, Tokars, Valerie, Zhou, Ya, Turlington, Mark, Saldanha, S. Adrian, Chase, Peter, Eggler, Aimee, Dawson, Eric S., Baez-Santos, Yahira M., Tomar, Sakshi, Mielech, Anna M., Baker, Susan C., Lindsley, Craig W., Hodder, Peter, Mesecar, Andrew, Stauffer, Shaun R.
Veröffentlicht 2013