Twenty years of G-CSF clinical and nonclinical discoveries /

por Molineux, G., Foote, MaryAnn., Arvedson, Tara.
Publicado em 2012

Design Rationale and Development Approach for Pegfilgrastim as a Long-Acting Granulocyte Colony-Stimulating Factor

por Arvedson, Tara, O’Kelly, James, Yang, Bing-Bing
Publicado no BioDrugs (2015)

Neogenin-mediated Hemojuvelin Shedding Occurs after Hemojuvelin Traffics to the Plasma Membrane

por Zhang, An-Sheng, Yang, Fan, Meyer, Kathrin, Hernandez, Catalina, Chapman-Arvedson, Tara, Bjorkman, Pamela J., Enns, Caroline A.
Publicado em 2008

Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

por Ross, Sandra L., Biswas, Kaustav, Rottman, James, Allen, Jennifer R., Long, Jason, Miranda, Les P., Winters, Aaron, Arvedson, Tara L.
Publicado no Front Pharmacol (2017)

Bispecific T cell engager (BiTE(®)) antibody constructs can mediate bystander tumor cell killing

por Ross, Sandra L., Sherman, Marika, McElroy, Patricia L., Lofgren, Julie A., Moody, Gordon, Baeuerle, Patrick A., Coxon, Angela, Arvedson, Tara
Publicado no PLoS One (2017)

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

por Billesbølle, Christian B., Azumaya, Caleigh M., Kretsch, Rachael C., Powers, Alexander S., Gonen, Shane, Schneider, Simon, Arvedson, Tara, Dror, Ron O., Cheng, Yifan, Manglik, Aashish
Publicado no Nature (2020)

Hepcidin Revisited, Disulfide Connectivity, Dynamics, and Structure

por Jordan, John B., Poppe, Leszek, Haniu, Mitsuru, Arvedson, Tara, Syed, Rashid, Li, Vivian, Kohno, Hiko, Kim, Helen, Schnier, Paul D., Harvey, Timothy S., Miranda, Les P., Cheetham, Janet, Sasu, Barbra J.
Publicado em 2009

Classical and intermediate monocytes scavenge non-transferrin-bound iron and damaged erythrocytes

por Haschka, David, Petzer, Verena, Kocher, Florian, Tschurtschenthaler, Christoph, Schaefer, Benedikt, Seifert, Markus, Sopper, Sieghart, Sonnweber, Thomas, Feistritzer, Clemens, Arvedson, Tara L., Zoller, Heinz, Stauder, Reinhard, Theurl, Igor, Weiss, Guenter, Tymoszuk, Piotr
Publicado no JCI Insight (2019)

Nonclinical Safety Assessment of AMG 553, an Investigational Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Acute Myeloid Leukemia

por Karbowski, Christine, Goldstein, Rebecca, Frank, Brendon, Kim, Kei, Li, Chi-Ming, Homann, Oliver, Hensley, Kelly, Brooks, Benjamin, Wang, Xiaoting, Yan, Qinghong, Hernandez, Rocio, Adams, Gregor, Boyle, Michael, Arvedson, Tara, Lebrec, Herve
Publicado no Toxicol Sci (2020)

The immunomodulatory drugs lenalidomide and pomalidomide enhance the potency of AMG 701 in multiple myeloma preclinical models

por Cho, Shih-Feng, Lin, Liang, Xing, Lijie, Li, Yuyin, Wen, Kenneth, Yu, Tengteng, Hsieh, Phillip A., Munshi, Nikhil, Wahl, Joachim, Matthes, Katja, Friedrich, Matthias, Arvedson, Tara, Anderson, Kenneth C., Tai, Yu-Tzu
Publicado no Blood Adv (2020)

AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeys

por Goldstein, Rebecca L., Goyos, Ana, Li, Chi-Ming, Deegen, Petra, Bogner, Pamela, Sternjak, Alexander, Thomas, Oliver, Klinger, Matthias, Wahl, Joachim, Friedrich, Matthias, Rattel, Benno, Lamas, Edwin, Min, Xiaoshan, Sudom, Athena, Farshbaf, Mozhgan, Coxon, Angela, Balazs, Mercedesz, Arvedson, Tara
Publicado no Blood Adv (2020)

Hepcidin regulation in prostate and its disruption in prostate cancer

por Tesfay, Lia, Clausen, Kathryn A., Kim, Jin W., Hegde, Poornima, Wang, Xiaohong, Miller, Lance D., Deng, Zhiyong, Blanchette, Nicole, Arvedson, Tara, Miranti, Cindy K., Babitt, Jodie L., Lin, Herbert Y., Peehl, Donna M., Torti, Frank M., Torti, Suzy V.
Publicado no Cancer Res (2015)

Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing

por Bessman, Nicholas J., Mathieu, Jacques R.R., Renassia, Cyril, Zhou, Lei, Fung, Thomas C., Fernandez, Keith C., Austin, Christine, Moeller, Jesper B., Zumerle, Sara, Louis, Sabine, Vaulont, Sophie, Ajami, Nadim J., Sokol, Harry, Putzel, Gregory G., Arvedson, Tara, Sockolow, Robbyn E., Lakhal-Littleon, Samira, Cloonan, Suzanne M., Arora, Manish, Peyssonnaux, Carole, Sonnenberg, Gregory F.
Publicado no Science (2020)

Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRAS(G12C)

por Shin, Youngsook, Jeong, Joon Won, Wurz, Ryan P., Achanta, Pragathi, Arvedson, Tara, Bartberger, Michael D., Campuzano, Iain D. G., Fucini, Ray, Hansen, Stig K., Ingersoll, John, Iwig, Jeffrey S., Lipford, J. Russell, Ma, Vu, Kopecky, David J., McCarter, John, San Miguel, Tisha, Mohr, Christopher, Sabet, Sudi, Saiki, Anne Y., Sawayama, Andrew, Sethofer, Steven, Tegley, Christopher M., Volak, Laurie P., Yang, Kevin, Lanman, Brian A., Erlanson, Daniel A., Cee, Victor J.
Publicado no ACS Med Chem Lett (2019)

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

por Theurl, Igor, Hilgendorf, Ingo, Nairz, Manfred, Tymoszuk, Piotr, Haschka, David, Asshoff, Malte, He, Shun, Gerhardt, Louisa M. S., Holderried, Tobias A. W., Seifert, Markus, Sopper, Sieghart, Fenn, Ashley M., Anzai, Atsushi, Rattik, Sara, McAlpine, Cameron, Theurl, Milan, Wieghofer, Peter, Iwamoto, Yoshiko, Weber, Georg F., Harder, Nina K., Chousterman, Benjamin G., Arvedson, Tara L., McKee, Mary, Wang, Fudi, Lutz, Oliver M. D., Rezoagli, Emanuele, Babitt, Jodie L., Berra, Lorenzo, Prinz, Marco, Nahrendorf, Matthias, Weiss, Guenter, Weissleder, Ralph, Lin, Herbert Y., Swirski, Filip K.
Publicado no Nat Med (2016)