Neogenin-mediated Hemojuvelin Shedding Occurs after Hemojuvelin Traffics to the Plasma Membrane

HFE2 (hemochromatosis type 2 gene) is highly expressed in skeletal muscle and liver hepatocytes. Its encoded protein, hemojuvelin (HJV), is a co-receptor for the bone morphogenetic proteins 2 and 4 (BMP2 and BMP4) and enhances the BMP-induced hepcidin expression. Hepcidin is a central iron regulator...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, An-Sheng, Yang, Fan, Meyer, Kathrin, Hernandez, Catalina, Chapman-Arvedson, Tara, Bjorkman, Pamela J., Enns, Caroline A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427329/
https://ncbi.nlm.nih.gov/pubmed/18445598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710527200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados