Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

The iron exporter ferroportin and its ligand, the hormone hepcidin, control fluxes of stored and recycled iron for use in a variety of essential biochemical processes. Inflammatory disorders and malignancies are often associated with high hepcidin levels, leading to ferroportin down-regulation, iron...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Ross, Sandra L., Biswas, Kaustav, Rottman, James, Allen, Jennifer R., Long, Jason, Miranda, Les P., Winters, Aaron, Arvedson, Tara L.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702341/
https://ncbi.nlm.nih.gov/pubmed/29209212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00838
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