A MEK Inhibitor Abrogates Myeloproliferative Disease in Kras Mutant Mice

Bằng Lyubynska, Natalya, Gorman, Matthew F., Lauchle, Jennifer O., Hong, Wan Xing, Akutagawa, Jon K., Shannon, Kevin, Braun, Benjamin S.
Được phát hành 2011

Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice

Bằng Chang, Tiffany, Krisman, Kimberly, Theobald, Emily Harding, Xu, Jin, Akutagawa, Jon, Lauchle, Jennifer O., Kogan, Scott, Braun, Benjamin S., Shannon, Kevin
Được phát hành 2012

Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice

Bằng Chang, Tiffany, Krisman, Kimberly, Theobald, Emily Harding, Xu, Jin, Akutagawa, Jon, Lauchle, Jennifer O., Kogan, Scott, Braun, Benjamin S., Shannon, Kevin
Xuất bản năm J Clin Invest (2016)

Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras

Bằng Akutagawa, Jon, Huang, Tannie Q., Epstein, Inbal, Chang, Tiffany, Quirindongo-Crespo, Maricel, Cottonham, Charisa L., Dail, Monique, Slusher, Barbara S., Friedman, Lori S., Sampath, Deepak, Braun, Benjamin S.
Xuất bản năm Leukemia (2016)

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

Bằng Stieglitz, Elliot, Mazor, Tali, Olshen, Adam B., Geng, Huimin, Gelston, Laura C., Akutagawa, Jon, Lipka, Daniel B., Plass, Christoph, Flotho, Christian, Chehab, Farid F., Braun, Benjamin S., Costello, Joseph F., Loh, Mignon L.
Xuất bản năm Nat Commun (2017)

BCL-2 IS A THERAPEUTIC TARGET FOR HYPODIPLOID B-LINEAGE ACUTE LYMPHOBLASTIC LEUKEMIA

Bằng Diaz-Flores, Ernesto, Comeaux, Evan Q., Kim, Kailyn L., Melnik, Ella, Beckman, Kyle, Davis, Kara L., Wu, Kevin, Akutagawa, Jon, Bridges, Olga, Marino, Roberta, Wohlfeil, Margo, Braun, Benjamin S., Mullighan, Charles G., Loh, Mignon L.
Xuất bản năm Cancer Res (2019)

Phospholipase C γ and Phosphoinositide 3-Kinase Link Cytokines to ERK Activation in Hematopoietic Cells With Normal and Oncogenic Kras

Bằng Diaz-Flores, Ernesto, Goldschmidt, Hana, Depeille, Philippe, Ng, Victor, Akutagawa, Jon, Krisman, Kimberly, Crone, Michael, Burgess, Michael R., Williams, Olusegun, Houseman, Benjamin, Shokat, Kevan, Sampath, Deepak, Bollag, Gideon, Roose, Jeroen P., Braun, Benjamin S., Shannon, Kevin
Được phát hành 2013

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment

Bằng Tran, Thai Hoa, Nguyen, Jonathan V., Stecula, Adrian, Akutagawa, Jon, Moorman, Anthony V., Braun, Benjamin S., Sali, Andrej, Mullighan, Charles G., Shah, Neil P., Dai, Yunfeng, Devidas, Meenakshi, Roberts, Kathryn G., Smith, Catherine C., Loh, Mignon L.
Xuất bản năm Haematologica (2021)

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia

Bằng Stieglitz, Elliot, Troup, Camille B., Gelston, Laura C., Haliburton, John, Chow, Eric D., Yu, Kristie B., Akutagawa, Jon, Taylor-Weiner, Amaro N., Liu, Y. Lucy, Wang, Yong-Dong, Beckman, Kyle, Emanuel, Peter D., Braun, Benjamin S., Abate, Adam, Gerbing, Robert B., Alonzo, Todd A., Loh, Mignon L.
Xuất bản năm Blood (2015)