Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative disorder of childhood caused by mutations in the Ras pathway. Outcomes in JMML vary markedly from spontaneous resolution to rapid relapse after hematopoietic stem cell transplantation. Here, we hypothesized that DNA methylation patterns...

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Publicat a:Nat Commun
Autors principals: Stieglitz, Elliot, Mazor, Tali, Olshen, Adam B., Geng, Huimin, Gelston, Laura C., Akutagawa, Jon, Lipka, Daniel B., Plass, Christoph, Flotho, Christian, Chehab, Farid F., Braun, Benjamin S., Costello, Joseph F., Loh, Mignon L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736624/
https://ncbi.nlm.nih.gov/pubmed/29259179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02178-9
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