International consensus definition of DNA methylation subgroups in juvenile myelomonocytic leukemia

PURPOSE: Known clinical and genetic markers have limitations in predicting disease course and outcome in juvenile myelomonocytic leukemia (JMML). DNA methylation (DNAme) patterns in JMML have correlated with outcome across multiple studies, suggesting it as a biomarker to improve patient stratificat...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Schönung, Maximilian, Meyer, Julia, Nöllke, Peter, Olshen, Adam, Hartmann, Mark, Murakami, Norihiro, Wakamatsu, Manabu, Okuno, Yusuke, Plass, Christoph, Loh, Mignon L., Niemeyer, Charlotte M., Muramatsu, Hideki, Flotho, Christian, Stieglitz, Elliot, Lipka, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785676/
https://ncbi.nlm.nih.gov/pubmed/33139265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-3184
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