International consensus definition of DNA methylation subgroups in juvenile myelomonocytic leukemia

PURPOSE: Known clinical and genetic markers have limitations in predicting disease course and outcome in juvenile myelomonocytic leukemia (JMML). DNA methylation (DNAme) patterns in JMML have correlated with outcome across multiple studies, suggesting it as a biomarker to improve patient stratificat...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Schönung, Maximilian, Meyer, Julia, Nöllke, Peter, Olshen, Adam, Hartmann, Mark, Murakami, Norihiro, Wakamatsu, Manabu, Okuno, Yusuke, Plass, Christoph, Loh, Mignon L., Niemeyer, Charlotte M., Muramatsu, Hideki, Flotho, Christian, Stieglitz, Elliot, Lipka, Daniel B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785676/
https://ncbi.nlm.nih.gov/pubmed/33139265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-3184
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