International consensus definition of DNA methylation subgroups in juvenile myelomonocytic leukemia

PURPOSE: Known clinical and genetic markers have limitations in predicting disease course and outcome in juvenile myelomonocytic leukemia (JMML). DNA methylation (DNAme) patterns in JMML have correlated with outcome across multiple studies, suggesting it as a biomarker to improve patient stratificat...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Schönung, Maximilian, Meyer, Julia, Nöllke, Peter, Olshen, Adam, Hartmann, Mark, Murakami, Norihiro, Wakamatsu, Manabu, Okuno, Yusuke, Plass, Christoph, Loh, Mignon L., Niemeyer, Charlotte M., Muramatsu, Hideki, Flotho, Christian, Stieglitz, Elliot, Lipka, Daniel B.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785676/
https://ncbi.nlm.nih.gov/pubmed/33139265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-3184
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