Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia

Juvenile myelomonocytic leukemia (JMML) is an aggressive myeloproliferative neoplasm of childhood associated with a poor prognosis. Recently, massively parallel sequencing has identified recurrent mutations in the SKI domain of SETBP1 in a variety of myeloid disorders. These lesions were detected in...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Blood
Glavni autori: Stieglitz, Elliot, Troup, Camille B., Gelston, Laura C., Haliburton, John, Chow, Eric D., Yu, Kristie B., Akutagawa, Jon, Taylor-Weiner, Amaro N., Liu, Y. Lucy, Wang, Yong-Dong, Beckman, Kyle, Emanuel, Peter D., Braun, Benjamin S., Abate, Adam, Gerbing, Robert B., Alonzo, Todd A., Loh, Mignon L.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2015
Teme:
Myeloid Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296011/
https://ncbi.nlm.nih.gov/pubmed/25395418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-601690
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items