PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization.

by Houslay, Miles D, Adams, David R
Published 2003

GENOME-SCALE SEQUENCING TO IDENTIFY GENES INVOLVED IN MENDELIAN DISORDERS

by Markello, Thomas C, Adams, David R
Published 2013

The National Institutes of Health undiagnosed diseases program

by Tifft, Cynthia J., Adams, David R.
Published in Curr Opin Pediatr (2014)

RACK1, A multifaceted scaffolding protein: Structure and function

by Adams, David R, Ron, Dorit, Kiely, Patrick A
Published 2011

Identifying Clinical Terms in Medical Text Using Ontology-Guided Machine Learning

by Arbabi, Aryan, Adams, David R, Fidler, Sanja, Brudno, Michael
Published in JMIR Med Inform (2019)

Biofilm-Specific Cross-Species Induction of Antimicrobial Compounds in Bacilli

by Yan, Liming, Boyd, Kenneth G., Adams, David R., Burgess, J. Grant
Published 2003

Serine Phosphorylation of the Insulin-like Growth Factor I (IGF-1) Receptor C-terminal Tail Restrains Kinase Activity and Cell Growth

by Kelly, Geraldine M., Buckley, Deirdre A., Kiely, Patrick A., Adams, David R., O'Connor, Rosemary
Published 2012

RACK(1) to the future – a historical perspective

by Ron, Dorit, Adams, David R, Baillie, George S, Long, Aideen, O’Connor, Rosemary, Kiely, Patrick A
Published 2013

The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation

by Barker, Graeme, Parnell, Euan, van Basten, Boy, Buist, Hanna, Adams, David R., Yarwood, Stephen J.
Published in J Cardiovasc Dev Dis (2017)

Direct Interaction between Scaffolding Proteins RACK1 and 14-3-3ζ Regulates Brain-derived Neurotrophic Factor (BDNF) Transcription

by Neasta, Jérémie, Kiely, Patrick A., He, Dao-Yao, Adams, David R., O'Connor, Rosemary, Ron, Dorit
Published 2012

Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners

by Houslay, Kirsty F., Christian, Frank, MacLeod, Ruth, Adams, David R., Houslay, Miles D., Baillie, George S.
Published in Biochem J (2017)

Limited Effects of Endurance or Interval Training on Visceral Adipose Tissue and Systemic Inflammation in Sedentary Middle-Aged Men

by Cooper, Joshua H. F., Collins, Blake E. G., Adams, David R., Robergs, Robert A., Donges, Cheyne E.
Published in J Obes (2016)

The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS): One Program’s Experience Developing Custom Software to Support Research for Complex-Disease Families

by Guzman, Jessica, Lee, Elizabeth, Draper, David, Valivullah, Zaheer, Yu, Guoyun, Sincan, Murat, Gahl, William A., Adams, David R.
Published in Children (Basel) (2015)

Genomewide significance testing of variation from single case exomes

by Wilfert, Amy B., Chao, Katherine R., Kaushal, Madhurima, Jain, Sanjay, Zöllner, Sebastian, Adams, David R., Conrad, Donald F.
Published in Nat Genet (2016)

Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb deletion in the OCA2 gene revealed a co-segregation of the controversial variant, p.R305W

by Gao, Jackson, D’Souza, Leera, Wetherby, Keith, Antolik, Christian, Reeves, Melissa, Adams, David R., Tumminia, Santa, Wang, Xinjing
Published in Cell Biosci (2017)

The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular...

by El Buri, Ashref, Adams, David R., Smith, Douglas, Tate, Rothwelle J., Mullin, Margaret, Pyne, Susan, Pyne, Nigel J.
Published in Oncotarget (2018)

Phosphorylation of RACK1 on Tyrosine 52 by c-Abl Is Required for Insulin-like Growth Factor I-mediated Regulation of Focal Adhesion Kinase

by Kiely, Patrick A., Baillie, George S., Barrett, Robert, Buckley, Deirdre A., Adams, David R., Houslay, Miles D., O'Connor, Rosemary
Published 2009

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

by Hudson, Brian D., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Kostenis, Evi, Adams, David R., Ulven, Trond, Milligan, Graeme
Published 2012

Free Sialic Acid Storage Disorder: Progress and Promise

by Huizing, Marjan, Hackbarth, Mary E., Adams, David R, Wasserstein, Melissa, Patterson, Marc C, Walkley, Steven U, Gahl, William A
Published in Neurosci Lett (2021)

MEK1 Binds Directly to βArrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization

by Meng, Dong, Lynch, Martin J., Huston, Elaine, Beyermann, Michael, Eichhorst, Jenny, Adams, David R., Klussmann, Enno, Houslay, Miles D., Baillie, George S.
Published 2009