Functionally Essential Tubular Proteins Are Lost to Urine-Excreted, Large Extracellular Vesicles during Chronic Renal Insufficiency

by Adam, Ryan J., Paterson, Mark R., Wardecke, Lukus, Hoffmann, Brian R., Kriegel, Alison J.
Published in Kidney360 (2020)

CFTR potentiation as a therapeutic strategy for pulmonary edema: a proof-of-concept study in pigs

by Li, Xiaopeng, Vargas Buonfiglio, Luis G., Adam, Ryan J., Stoltz, David A., Zabner, Joseph, Comellas, Alejandro P.
Published in Crit Care Med (2017)

Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure

by Adam, Ryan J., Xia, Zhiqiu, Pravoverov, Kristina, Hong, Juan, Case, Adam J., Schultz, Harold D., Lisco, Steven J., Zucker, Irving H., Wang, Han-Jun
Published in Am J Physiol Heart Circ Physiol (2019)

Mounier–Kuhn syndrome: a case of tracheal smooth muscle remodeling

by Cook, Daniel P., Adam, Ryan J., Abou Alaiwa, Mahmoud H., Eberlein, Michael, Klesney‐Tait, Julia A., Parekh, Kalpaj R., Meyerholz, David K., Stoltz, David A.
Published in Clin Case Rep (2016)

CF airway smooth muscle transcriptome reveals a role for PYK2

by Cook, Daniel P., Adam, Ryan J., Zarei, Keyan, Deonovic, Benjamin, Stroik, Mallory R., Gansemer, Nicholas D., Meyerholz, David K., Au, Kin Fai, Stoltz, David A.
Published in JCI Insight (2017)

Macrophage activation in stellate ganglia contributes to lung injury-induced arrhythmogenesis in male rats

by Hong, Juan, Adam, Ryan J., Gao, Lie, Hahka, Taija, Xia, Zhiqiu, Wang, Dong, Nicholas, Thomas A., Zucker, Irving H., Lisco, Steven J., Wang, Han-Jun
Published in Acta Physiol (Oxf) (2021)

Tracheomalacia is associated with lower FEV(1) and Pseudomonas acquisition in children with CF

by Fischer, Anthony J., Singh, Sachinkumar B., Adam, Ryan J., Stoltz, David A., Baranano, Christopher F., Kao, Simon, Weinberger, Miles M., McCray, Paul B., Starner, Timothy D.
Published in Pediatr Pulmonol (2013)

Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice

by Reznikov, Leah R., Meyerholz, David K., Adam, Ryan J., Abou Alaiwa, Mahmoud, Jaffer, Omar, Michalski, Andrew S., Powers, Linda S., Price, Margaret P., Stoltz, David A., Welsh, Michael J.
Published in PLoS One (2016)

Integrin α6β4 Identifies Human Distal Lung Epithelial Progenitor Cells with Potential as a Cell-Based Therapy for Cystic Fibrosis Lung Disease

by Li, Xiaopeng, Rossen, Nathan, Sinn, Patrick L., Hornick, Andrew L., Steines, Benjamin R., Karp, Philip H., Ernst, Sarah E., Adam, Ryan J., Moninger, Thomas O., Levasseur, Dana N., Zabner, Joseph
Published 2013

SONOGRAPHIC EVIDENCE OF ABNORMAL TRACHEAL CARTILAGE RING STRUCTURE IN CYSTIC FIBROSIS

by Diwakar, Amit, Adam, Ryan J., Michalski, Andrew S., Tamegnon, Monelle M., Fischer, Anthony J., Launspach, Jan L., Horan, Rebecca A., Kao, Simon C., Chaloner, Kathryn, Meyerholz, David K., Stoltz, David A.
Published in Laryngoscope (2015)

Early Airway Structural Changes in Cystic Fibrosis Pigs as a Determinant of Particle Distribution and Deposition

by Awadalla, Maged, Miyawaki, Shinjiro, Alaiwa, Mahmoud H. Abou, Adam, Ryan J., Bouzek, Drake C., Michalski, Andrew S., Fuld, Matthew K., Reynolds, Karen J., Hoffman, Eric A., Lin, Ching-Long, Stoltz, David A.
Published 2013

Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs

by Hoegger, Mark J., Awadalla, Maged, Namati, Eman, Itani, Omar A., Fischer, Anthony J., Tucker, Alexander J., Adam, Ryan J., McLennan, Geoffrey, Hoffman, Eric A., Stoltz, David A., Welsh, Michael J.
Published 2014

Postnatal airway growth in cystic fibrosis piglets

by Adam, Ryan J., Abou Alaiwa, Mahmoud H., Bouzek, Drake C., Cook, Daniel P., Gansemer, Nicholas D., Taft, Peter J., Powers, Linda S., Stroik, Mallory R., Hoegger, Mark J., McMenimen, James D., Hoffman, Eric A., Zabner, Joseph, Welsh, Michael J., Meyerholz, David K., Stoltz, David A.
Published in J Appl Physiol (1985) (2017)

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs

by Meyerholz, David K., Stoltz, David A., Gansemer, Nick D., Ernst, Sarah E., Cook, Daniel P., Strub, Matthew D., LeClair, Erica N., Barker, Carrie K., Adam, Ryan J., Leidinger, Mariah R., Gibson-Corley, Katherine N., Karp, Philip H., Welsh, Michael J., McCray, Paul B.
Published in Lab Invest (2018)

Air Trapping and Airflow Obstruction in Newborn Cystic Fibrosis Piglets

by Adam, Ryan J., Michalski, Andrew S., Bauer, Christian, Abou Alaiwa, Mahmoud H., Gross, Thomas J., Awadalla, Maged S., Bouzek, Drake C., Gansemer, Nicholas D., Taft, Peter J., Hoegger, Mark J., Diwakar, Amit, Ochs, Matthias, Reinhardt, Joseph M., Hoffman, Eric A., Beichel, Reinhard R., Meyerholz, David K., Stoltz, David A.
Published 2013

Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities

by Adam, Ryan J., Hisert, Katherine B., Dodd, Jonathan D., Grogan, Brenda, Launspach, Janice L., Barnes, Janel K., Gallagher, Charles G., Sieren, Jered P., Gross, Thomas J., Fischer, Anthony J., Cavanaugh, Joseph E., Hoffman, Eric A., Singh, Pradeep K., Welsh, Michael J., McKone, Edward F., Stoltz, David A.
Published in JCI Insight (2016)

Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections

by Hisert, Katherine B., Heltshe, Sonya L., Pope, Christopher, Jorth, Peter, Wu, Xia, Edwards, Rachael M., Radey, Matthew, Accurso, Frank J., Wolter, Daniel J., Cooke, Gordon, Adam, Ryan J., Carter, Suzanne, Grogan, Brenda, Launspach, Janice L., Donnelly, Seamas C., Gallagher, Charles G., Bruce, James E., Stoltz, David A., Welsh, Michael J., Hoffman, Lucas R., McKone, Edward F., Singh, Pradeep K.
Published in Am J Respir Crit Care Med (2017)

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs

by Stoltz, David A., Rokhlina, Tatiana, Ernst, Sarah E., Pezzulo, Alejandro A., Ostedgaard, Lynda S., Karp, Philip H., Samuel, Melissa S., Reznikov, Leah R., Rector, Michael V., Gansemer, Nicholas D., Bouzek, Drake C., Alaiwa, Mahmoud H. Abou, Hoegger, Mark J., Ludwig, Paula S., Taft, Peter J., Wallen, Tanner J., Wohlford-Lenane, Christine, McMenimen, James D., Chen, Jeng-Haur, Bogan, Katrina L., Adam, Ryan J., Hornick, Emma E., Nelson, George A., Hoffman, Eric A., Chang, Eugene H., Zabner, Joseph, McCray, Paul B., Prather, Randall S., Meyerholz, David K., Welsh, Michael J.
Published 2013