Functionally Essential Tubular Proteins Are Lost to Urine-Excreted, Large Extracellular Vesicles during Chronic Renal Insufficiency

Por Adam, Ryan J., Paterson, Mark R., Wardecke, Lukus, Hoffmann, Brian R., Kriegel, Alison J.
Publicado no Kidney360 (2020)

CFTR potentiation as a therapeutic strategy for pulmonary edema: a proof-of-concept study in pigs

Por Li, Xiaopeng, Vargas Buonfiglio, Luis G., Adam, Ryan J., Stoltz, David A., Zabner, Joseph, Comellas, Alejandro P.
Publicado no Crit Care Med (2017)

Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure

Por Adam, Ryan J., Xia, Zhiqiu, Pravoverov, Kristina, Hong, Juan, Case, Adam J., Schultz, Harold D., Lisco, Steven J., Zucker, Irving H., Wang, Han-Jun
Publicado no Am J Physiol Heart Circ Physiol (2019)

Mounier–Kuhn syndrome: a case of tracheal smooth muscle remodeling

Por Cook, Daniel P., Adam, Ryan J., Abou Alaiwa, Mahmoud H., Eberlein, Michael, Klesney‐Tait, Julia A., Parekh, Kalpaj R., Meyerholz, David K., Stoltz, David A.
Publicado no Clin Case Rep (2016)

CF airway smooth muscle transcriptome reveals a role for PYK2

Por Cook, Daniel P., Adam, Ryan J., Zarei, Keyan, Deonovic, Benjamin, Stroik, Mallory R., Gansemer, Nicholas D., Meyerholz, David K., Au, Kin Fai, Stoltz, David A.
Publicado no JCI Insight (2017)

Macrophage activation in stellate ganglia contributes to lung injury-induced arrhythmogenesis in male rats

Por Hong, Juan, Adam, Ryan J., Gao, Lie, Hahka, Taija, Xia, Zhiqiu, Wang, Dong, Nicholas, Thomas A., Zucker, Irving H., Lisco, Steven J., Wang, Han-Jun
Publicado no Acta Physiol (Oxf) (2021)

Tracheomalacia is associated with lower FEV(1) and Pseudomonas acquisition in children with CF

Por Fischer, Anthony J., Singh, Sachinkumar B., Adam, Ryan J., Stoltz, David A., Baranano, Christopher F., Kao, Simon, Weinberger, Miles M., McCray, Paul B., Starner, Timothy D.
Publicado no Pediatr Pulmonol (2013)

Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice

Por Reznikov, Leah R., Meyerholz, David K., Adam, Ryan J., Abou Alaiwa, Mahmoud, Jaffer, Omar, Michalski, Andrew S., Powers, Linda S., Price, Margaret P., Stoltz, David A., Welsh, Michael J.
Publicado no PLoS One (2016)

Integrin α6β4 Identifies Human Distal Lung Epithelial Progenitor Cells with Potential as a Cell-Based Therapy for Cystic Fibrosis Lung Disease

Por Li, Xiaopeng, Rossen, Nathan, Sinn, Patrick L., Hornick, Andrew L., Steines, Benjamin R., Karp, Philip H., Ernst, Sarah E., Adam, Ryan J., Moninger, Thomas O., Levasseur, Dana N., Zabner, Joseph
Publicado em 2013

SONOGRAPHIC EVIDENCE OF ABNORMAL TRACHEAL CARTILAGE RING STRUCTURE IN CYSTIC FIBROSIS

Por Diwakar, Amit, Adam, Ryan J., Michalski, Andrew S., Tamegnon, Monelle M., Fischer, Anthony J., Launspach, Jan L., Horan, Rebecca A., Kao, Simon C., Chaloner, Kathryn, Meyerholz, David K., Stoltz, David A.
Publicado no Laryngoscope (2015)

Early Airway Structural Changes in Cystic Fibrosis Pigs as a Determinant of Particle Distribution and Deposition

Por Awadalla, Maged, Miyawaki, Shinjiro, Alaiwa, Mahmoud H. Abou, Adam, Ryan J., Bouzek, Drake C., Michalski, Andrew S., Fuld, Matthew K., Reynolds, Karen J., Hoffman, Eric A., Lin, Ching-Long, Stoltz, David A.
Publicado em 2013

Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs

Por Hoegger, Mark J., Awadalla, Maged, Namati, Eman, Itani, Omar A., Fischer, Anthony J., Tucker, Alexander J., Adam, Ryan J., McLennan, Geoffrey, Hoffman, Eric A., Stoltz, David A., Welsh, Michael J.
Publicado em 2014

Postnatal airway growth in cystic fibrosis piglets

Por Adam, Ryan J., Abou Alaiwa, Mahmoud H., Bouzek, Drake C., Cook, Daniel P., Gansemer, Nicholas D., Taft, Peter J., Powers, Linda S., Stroik, Mallory R., Hoegger, Mark J., McMenimen, James D., Hoffman, Eric A., Zabner, Joseph, Welsh, Michael J., Meyerholz, David K., Stoltz, David A.
Publicado no J Appl Physiol (1985) (2017)

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs

Por Meyerholz, David K., Stoltz, David A., Gansemer, Nick D., Ernst, Sarah E., Cook, Daniel P., Strub, Matthew D., LeClair, Erica N., Barker, Carrie K., Adam, Ryan J., Leidinger, Mariah R., Gibson-Corley, Katherine N., Karp, Philip H., Welsh, Michael J., McCray, Paul B.
Publicado no Lab Invest (2018)

Air Trapping and Airflow Obstruction in Newborn Cystic Fibrosis Piglets

Por Adam, Ryan J., Michalski, Andrew S., Bauer, Christian, Abou Alaiwa, Mahmoud H., Gross, Thomas J., Awadalla, Maged S., Bouzek, Drake C., Gansemer, Nicholas D., Taft, Peter J., Hoegger, Mark J., Diwakar, Amit, Ochs, Matthias, Reinhardt, Joseph M., Hoffman, Eric A., Beichel, Reinhard R., Meyerholz, David K., Stoltz, David A.
Publicado em 2013

Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities

Por Adam, Ryan J., Hisert, Katherine B., Dodd, Jonathan D., Grogan, Brenda, Launspach, Janice L., Barnes, Janel K., Gallagher, Charles G., Sieren, Jered P., Gross, Thomas J., Fischer, Anthony J., Cavanaugh, Joseph E., Hoffman, Eric A., Singh, Pradeep K., Welsh, Michael J., McKone, Edward F., Stoltz, David A.
Publicado no JCI Insight (2016)

Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections

Por Hisert, Katherine B., Heltshe, Sonya L., Pope, Christopher, Jorth, Peter, Wu, Xia, Edwards, Rachael M., Radey, Matthew, Accurso, Frank J., Wolter, Daniel J., Cooke, Gordon, Adam, Ryan J., Carter, Suzanne, Grogan, Brenda, Launspach, Janice L., Donnelly, Seamas C., Gallagher, Charles G., Bruce, James E., Stoltz, David A., Welsh, Michael J., Hoffman, Lucas R., McKone, Edward F., Singh, Pradeep K.
Publicado no Am J Respir Crit Care Med (2017)

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs

Por Stoltz, David A., Rokhlina, Tatiana, Ernst, Sarah E., Pezzulo, Alejandro A., Ostedgaard, Lynda S., Karp, Philip H., Samuel, Melissa S., Reznikov, Leah R., Rector, Michael V., Gansemer, Nicholas D., Bouzek, Drake C., Alaiwa, Mahmoud H. Abou, Hoegger, Mark J., Ludwig, Paula S., Taft, Peter J., Wallen, Tanner J., Wohlford-Lenane, Christine, McMenimen, James D., Chen, Jeng-Haur, Bogan, Katrina L., Adam, Ryan J., Hornick, Emma E., Nelson, George A., Hoffman, Eric A., Chang, Eugene H., Zabner, Joseph, McCray, Paul B., Prather, Randall S., Meyerholz, David K., Welsh, Michael J.
Publicado em 2013