Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs

Loss of cystic fibrosis transmembrane conductance regulator (CFTR) function causes cystic fibrosis (CF), predisposing the lungs to chronic infection and inflammation. In young infants with CF, structural airway defects are increasingly recognized before the onset of significant lung disease, which s...

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Bibliografiska uppgifter
I publikationen:Lab Invest
Huvudupphovsmän: Meyerholz, David K., Stoltz, David A., Gansemer, Nick D., Ernst, Sarah E., Cook, Daniel P., Strub, Matthew D., LeClair, Erica N., Barker, Carrie K., Adam, Ryan J., Leidinger, Mariah R., Gibson-Corley, Katherine N., Karp, Philip H., Welsh, Michael J., McCray, Paul B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019641/
https://ncbi.nlm.nih.gov/pubmed/29467455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0026-7
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