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CFTR potentiation as a therapeutic strategy for pulmonary edema: a proof-of-concept study in pigs
OBJECTIVE: To determine the feasibility of using a CFTR potentiator, ivacaftor (VX-770, Kayledeco®), as a therapeutic strategy for treating pulmonary edema. DESIGN: Prospective laboratory animal investigation. SETTING: Animal research laboratory. SUBJECTS: Newborn and 3-day to 1-week old pigs. INTER...
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| Publicado no: | Crit Care Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693779/ https://ncbi.nlm.nih.gov/pubmed/28953499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000002720 |
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