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Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense

While pathological and clinical data suggest that small airways are involved in early cystic fibrosis (CF) lung disease development, little is known about how the lack of cystic fibrosis transmembrane conductance regulator (CFTR) function contributes to disease pathogenesis in these small airways. L...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Li, Xiaopeng, Tang, Xiao Xiao, Vargas Buonfiglio, Luis G., Comellas, Alejandro P., Thornell, Ian M., Ramachandran, Shyam, Karp, Philip H., Taft, Peter J., Sheets, Kelsey, Abou Alaiwa, Mahmoud H., Welsh, Michael J., Meyerholz, David K., Stoltz, David A., Zabner, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824164/
https://ncbi.nlm.nih.gov/pubmed/26801568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00422.2015
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