hMSH2 expression is driven by AP1-dependent regulation through phorbol-ester exposure

Por Humbert, Odile, Achour, Ikbel, Lautier, Dominique, Laurent, Guy, Salles, Bernard
Publicado em 2003

Three dimensional architecture of the Igh locus facilitates class switch recombination

Por Kenter, Amy L., Feldman, Scott, Wuerffel, Robert, Achour, Ikbel, Wang, Lili, Kumar, Satyendra
Publicado em 2012

Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

Por Gardeux, Vincent, Arslan, Ahmet D, Achour, Ikbel, Ho, Tsui-Ting, Beck, William T, Lussier, Yves A
Publicado em 2014

Constraints contributed by chromatin looping limit recombination targeting during immunoglobulin class switch recombination

Por Feldman, Scott, Achour, Ikbel, Wuerffel, Robert, Kumar, Satyendra, Gerasimova, Tatiana, Sen, Ranjan, Kenter, Amy L.
Publicado no J Immunol (2015)

Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival

Por Schissler, A. Grant, Gardeux, Vincent, Li, Qike, Achour, Ikbel, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Publicado no Bioinformatics (2015)

Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny

Por Kumar, Satyendra, Wuerffel, Robert, Achour, Ikbel, Lajoie, Bryan, Sen, Ranjan, Dekker, Job, Feeney, Ann J., Kenter, Amy L.
Publicado em 2013

In Silico cancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy as...

Por Yang, Xinan, Huang, Yong, Lee, Younghee, Gardeux, Vincent, Achour, Ikbel, Regan, Kelly, Rebman, Ellen, Li, Haiquan, Lussier, Yves A
Publicado em 2014

kMEn: analyzing noisy and bidirectional transcriptional pathway responses in single subjects

Por Li, Qike, Schissler, A. Grant, Gardeux, Vincent, Berghout, Joanne, Achour, Ikbel, Kenost, Colleen, Li, Haiquan, Zhang, Hao Helen, Lussier, Yves A.
Publicado no J Biomed Inform (2016)

Analysis of aggregated cell–cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells

Por Schissler, A. Grant, Li, Qike, Chen, James L., Kenost, Colleen, Achour, Ikbel, Billheimer, D. Dean, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Publicado no Bioinformatics (2016)

eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs

Por Li, Haiquan, Pouladi, Nima, Achour, Ikbel, Gardeux, Vincent, Li, Jianrong, Li, Qike, Zhang, Hao Helen, Martinez, Fernando D., Garcia, Joe G.N. ‘Skip’, Lussier, Yves A.
Publicado no J Biomed Inform (2015)

Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases

Por Lee, Younghee, Li, Haiquan, Li, Jianrong, Rebman, Ellen, Achour, Ikbel, Regan, Kelly E, Gamazon, Eric R, Chen, James L, Yang, Xinan Holly, Cox, Nancy J, Lussier, Yves A
Publicado em 2013

‘N-of-1-pathways’ unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine

Por Gardeux, Vincent, Achour, Ikbel, Li, Jianrong, Maienschein-Cline, Mark, Li, Haiquan, Pesce, Lorenzo, Parinandi, Gurunadh, Bahroos, Neil, Winn, Robert, Foster, Ian, Garcia, Joe G N, Lussier, Yves A
Publicado em 2014

The discriminatory cost of ICD-10-CM transition between clinical specialties: metrics, case study, and mitigating tools

Por Boyd, Andrew D, Li, Jianrong ‘John’, Burton, Mike D, Jonen, Michael, Gardeux, Vincent, Achour, Ikbel, Luo, Roger Q, Zenku, Ilir, Bahroos, Neil, Brown, Stephen B, Vanden Hoek, Terry, Lussier, Yves A
Publicado em 2013

Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions

Por Li, Haiquan, Achour, Ikbel, Bastarache, Lisa, Berghout, Joanne, Gardeux, Vincent, Li, Jianrong, Lee, Younghee, Pesce, Lorenzo, Yang, Xinan, Ramos, Kenneth S, Foster, Ian, Denny, Joshua C, Moore, Jason H, Lussier, Yves A
Publicado no NPJ Genom Med (2016)

Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform

Por Klarenbeek, Alex, Mazouari, Khalil El, Desmyter, Aline, Blanchetot, Christophe, Hultberg, Anna, de Jonge, Natalie, Roovers, Rob C, Cambillau, Christian, Spinelli, Sylvia, Del-Favero, Jurgen, Verrips, Theo, de Haard, Hans J, Achour, Ikbel
Publicado no MAbs (2015)