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Constraints contributed by chromatin looping limit recombination targeting during immunoglobulin class switch recombination

Engagement of promoters with distal elements in long range looping interactions has been implicated in regulation of Ig class switch recombination (CSR). The principles determining the spatial and regulatory relationships among Igh transcriptional elements remain poorly defined. We examined the chro...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Feldman, Scott, Achour, Ikbel, Wuerffel, Robert, Kumar, Satyendra, Gerasimova, Tatiana, Sen, Ranjan, Kenter, Amy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440573/
https://ncbi.nlm.nih.gov/pubmed/25624452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401170
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