Constraints contributed by chromatin looping limit recombination targeting during immunoglobulin class switch recombination

Engagement of promoters with distal elements in long range looping interactions has been implicated in regulation of Ig class switch recombination (CSR). The principles determining the spatial and regulatory relationships among Igh transcriptional elements remain poorly defined. We examined the chro...

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Bibliographic Details
Published in:J Immunol
Main Authors: Feldman, Scott, Achour, Ikbel, Wuerffel, Robert, Kumar, Satyendra, Gerasimova, Tatiana, Sen, Ranjan, Kenter, Amy L.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440573/
https://ncbi.nlm.nih.gov/pubmed/25624452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401170
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