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Three dimensional architecture of the Igh locus facilitates class switch recombination
Immunoglobulin (Ig) class switch recombination (CSR) is responsible for diversification of antibody effector function during an immune response. This region specific recombination event, between repetitive switch (S) DNA elements, is unique to B lymphocytes and is induced by activation induced deami...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442954/ https://ncbi.nlm.nih.gov/pubmed/22954221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06604.x |
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