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Three dimensional architecture of the Igh locus facilitates class switch recombination

Immunoglobulin (Ig) class switch recombination (CSR) is responsible for diversification of antibody effector function during an immune response. This region specific recombination event, between repetitive switch (S) DNA elements, is unique to B lymphocytes and is induced by activation induced deami...

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Detalhes bibliográficos
Main Authors: Kenter, Amy L., Feldman, Scott, Wuerffel, Robert, Achour, Ikbel, Wang, Lili, Kumar, Satyendra
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442954/
https://ncbi.nlm.nih.gov/pubmed/22954221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06604.x
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