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53BP1 contributes to Igh locus chromatin topology during class switch recombination
In B lymphocytes, immunoglobulin class switch recombination (CSR) is induced by activation induced cytidine deaminase (AID) which initiates a cascade of events leading to DNA double stand break (DSB) formation in switch (S) regions. Resolution of DSBs proceeds through formation of S-S synaptic compl...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5695034/ https://ncbi.nlm.nih.gov/pubmed/28159901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601947 |
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