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S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination

Immunoglobulin class switch recombination is governed by long-range interactions between enhancers and germline transcript promoters to activate transcription and modulate chromatin accessibility to activation-induced cytidine deaminase (AID). However, mechanisms leading to the differential targetin...

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Hlavní autoři: Wang, Lili, Wuerffel, Robert, Feldman, Scott, Khamlichi, Ahmed Amine, Kenter, Amy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722165/
https://ncbi.nlm.nih.gov/pubmed/19596805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081678
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