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Switch Region Identity Plays an Important Role in Ig Class Switch Recombination

Ig class switch recombination (CSR) is regulated through long-range intrachromosomal interactions between germline transcript promoters and enhancers to initiate transcription and create chromatin accessible to activation-induced deaminase attack. CSR occurs between switch (S) regions that flank Cμ...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Bhattacharya, Palash, Wuerffel, Robert, Kenter, Amy L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979553/
https://ncbi.nlm.nih.gov/pubmed/20427773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000507
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