In Silico cancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy assessment

BACKGROUND: The current state of the art for measuring stromal response to targeted therapy requires burdensome and rate limiting quantitative histology. Transcriptome measures are increasingly affordable and provide an opportunity for developing a stromal versus cancer ratio in xenograft models. In...

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Detalhes bibliográficos
Main Authors: Yang, Xinan, Huang, Yong, Lee, Younghee, Gardeux, Vincent, Achour, Ikbel, Regan, Kelly, Rebman, Ellen, Li, Haiquan, Lussier, Yves A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101338/
https://ncbi.nlm.nih.gov/pubmed/25079962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-7-S1-S2
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