Complex-disease networks of trait-associated single-nucleotide polymorphisms (SNPs) unveiled by information theory

OBJECTIVE: Thousands of complex-disease single-nucleotide polymorphisms (SNPs) have been discovered in genome-wide association studies (GWAS). However, these intragenic SNPs have not been collectively mined to unveil the genetic architecture between complex clinical traits. The authors hypothesize t...

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Main Authors: Li, Haiquan, Lee, Younghee, Chen, James L, Rebman, Ellen, Li, Jianrong, Lussier, Yves A
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2012
Teme:
Research and Applications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277620/
https://ncbi.nlm.nih.gov/pubmed/22278381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2011-000482
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