Combining site-specific mutagenesis and seeding as a strategy to crystallize ‘difficult’ proteins: the case of Staphylococcus aureus thioredoxin

Por Roos, Goedele, Brosens, Elke, Wahni, Khadija, Desmyter, Aline, Spinelli, Silvia, Wyns, Lode, Messens, Joris, Loris, Remy
Publicado em 2006

Viral infection modulation and neutralization by camelid nanobodies

Por Desmyter, Aline, Farenc, Carine, Mahony, Jennifer, Spinelli, Silvia, Bebeacua, Cecilia, Blangy, Stéphanie, Veesler, David, van Sinderen, Douwe, Cambillau, Christian
Publicado em 2013

Production, crystallization and X-ray diffraction analysis of a complex between a fragment of the TssM T6SS protein and a camelid nanobody

Por Nguyen, Van Son, Spinelli, Silvia, Desmyter, Aline, Le, Thi Thu Hang, Kellenberger, Christine, Cascales, Eric, Cambillau, Christian, Roussel, Alain
Publicado no Acta Crystallogr F Struct Biol Commun (2015)

Receptor-Binding Protein of Lactococcus lactis Phages: Identification and Characterization of the Saccharide Receptor-Binding Site

Por Tremblay, Denise M., Tegoni, Mariella, Spinelli, Silvia, Campanacci, Valérie, Blangy, Stéphanie, Huyghe, Céline, Desmyter, Aline, Labrie, Steve, Moineau, Sylvain, Cambillau, Christian
Publicado em 2006

All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade

Por Messens, Joris, Martins, José C., Van Belle, Karolien, Brosens, Elke, Desmyter, Aline, De Gieter, Marjan, Wieruszeski, Jean-Michel, Willem, Rudolph, Wyns, Lode, Zegers, Ingrid
Publicado em 2002

Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody

Por Nguyen, Van Son, Logger, Laureen, Spinelli, Silvia, Desmyter, Aline, Le, Thi Thu Hang, Kellenberger, Christine, Douzi, Badreddine, Durand, Eric, Roussel, Alain, Cascales, Eric, Cambillau, Christian
Publicado no PLoS One (2015)

The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules

Por Legrand, Pierre, Collins, Barry, Blangy, Stéphanie, Murphy, James, Spinelli, Silvia, Gutierrez, Carlos, Richet, Nicolas, Kellenberger, Christine, Desmyter, Aline, Mahony, Jennifer, van Sinderen, Douwe, Cambillau, Christian
Publicado no mBio (2016)

Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies

Por Blanchetot, Christophe, De Jonge, Natalie, Desmyter, Aline, Ongenae, Nico, Hofman, Erik, Klarenbeek, Alex, Sadi, Ava, Hultberg, Anna, Kretz-Rommel, Anke, Spinelli, Silvia, Loris, Remy, Cambillau, Christian, de Haard, Hans
Publicado no J Biol Chem (2016)

Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase

Por Conrath, Katja, Pereira, Alice S, Martins, Carlos E, Timóteo, Cristina G, Tavares, Pedro, Spinelli, Silvia, Kinne, Joerg, Flaudrops, Christophe, Cambillau, Christian, Muyldermans, Serge, Moura, Isabel, Moura, Jose J G, Tegoni, Mariella, Desmyter, Aline
Publicado em 2009

Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform

Por Klarenbeek, Alex, Mazouari, Khalil El, Desmyter, Aline, Blanchetot, Christophe, Hultberg, Anna, de Jonge, Natalie, Roovers, Rob C, Cambillau, Christian, Spinelli, Sylvia, Del-Favero, Jurgen, Verrips, Theo, de Haard, Hans J, Achour, Ikbel
Publicado no MAbs (2015)