Developing an Enzyme-Assisted Derivatization Method for Analysis of C(27) Bile Alcohols and Acids by Electrospray Ionization-Mass Spectrometry

von Abdel-Khalik, Jonas, Crick, Peter J., Yutuc, Eylan, Wang, Yuqin, Griffiths, William J.
Veröffentlicht in Molecules (2019)

Current trends in oxysterol research

von Griffiths, William J., Abdel-Khalik, Jonas, Hearn, Thomas, Yutuc, Eylan, Morgan, Alwena H., Wang, Yuqin
Veröffentlicht in Biochem Soc Trans (2016)

Studies on the analysis of 25-hydroxyvitamin D(3) by isotope-dilution liquid chromatography–tandem mass spectrometry using enzyme-assisted derivatisation

von Abdel-Khalik, Jonas, Crick, Peter J., Carter, Graham D., Makin, Hugh L., Wang, Yuqin, Griffiths, William J.
Veröffentlicht 2014

Cholesterolomics: An update

von Griffiths, William J., Abdel-Khalik, Jonas, Yutuc, Eylan, Morgan, Alwena H., Gilmore, Ian, Hearn, Thomas, Wang, Yuqin
Veröffentlicht in Anal Biochem (2017)

Charge-tagging liquid chromatography–mass spectrometry methodology targeting oxysterol diastereoisomers

von Griffiths, William J., Hearn, Thomas, Crick, Peter J., Abdel-Khalik, Jonas, Dickson, Alison, Yutuc, Eylan, Wang, Yuqin
Veröffentlicht in Chem Phys Lipids (2017)

Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients

von Griffiths, William J., Abdel-Khalik, Jonas, Yutuc, Eylan, Roman, Gustavo, Warner, Margaret, Gustafsson, Jan-Åke, Wang, Yuqin
Veröffentlicht in Free Radic Biol Med (2019)

Cholesterol metabolites exported from human brain

von Iuliano, Luigi, Crick, Peter J., Zerbinati, Chiara, Tritapepe, Luigi, Abdel-Khalik, Jonas, Poirot, Marc, Wang, Yuqin, Griffiths, William J.
Veröffentlicht in Steroids (2015)

Reduced Plasma Levels of 25-Hydroxycholesterol and Increased Cerebrospinal Fluid Levels of Bile Acid Precursors in Multiple Sclerosis Patients

von Crick, Peter J., Griffiths, William J., Zhang, Juan, Beibel, Martin, Abdel-Khalik, Jonas, Kuhle, Jens, Sailer, Andreas W., Wang, Yuqin
Veröffentlicht in Mol Neurobiol (2016)

Formation and metabolism of oxysterols and cholestenoic acids found in the mouse circulation: Lessons learnt from deuterium-enrichment experiments and the CYP46A1 transgenic mouse

von Crick, Peter J., Yutuc, Eylan, Abdel-Khalik, Jonas, Saeed, Ahmed, Betsholtz, Christer, Genove, Guillem, Björkhem, Ingemar, Wang, Yuqin, Griffiths, William J.
Veröffentlicht in J Steroid Biochem Mol Biol (2019)

Identification of 7α,24-dihydroxy-3-oxocholest-4-en-26-oic and 7α,25-dihydroxy-3-oxocholest-4-en-26-oic acids in human cerebrospinal fluid and plasma

von Abdel-Khalik, Jonas, Crick, Peter J., Yutuc, Eylan, DeBarber, Andrea E., Duell, P. Barton, Steiner, Robert D., Laina, Ioanna, Wang, Yuqin, Griffiths, William J.
Veröffentlicht in Biochimie (2018)

Defective cholesterol metabolism in amyotrophic lateral sclerosis

von Abdel-Khalik, Jonas, Yutuc, Eylan, Crick, Peter J., Gustafsson, Jan-Åke, Warner, Margaret, Roman, Gustavo, Talbot, Kevin, Gray, Elizabeth, Griffiths, William J., Turner, Martin R., Wang, Yuqin
Veröffentlicht in J Lipid Res (2017)

Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma

von Griffiths, William J., Crick, Peter J., Meljon, Anna, Theofilopoulos, Spyridon, Abdel-Khalik, Jonas, Yutuc, Eylan, Parker, Josie E., Kelly, Diane E., Kelly, Steven L., Arenas, Ernest, Wang, Yuqin
Veröffentlicht in Biochim Biophys Acta Mol Cell Biol Lipids (2019)

24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo

von Theofilopoulos, Spyridon, Abreu de Oliveira, Willy Antoni, Yang, Shanzheng, Yutuc, Eylan, Saeed, Ahmed, Abdel-Khalik, Jonas, Ullgren, Abbe, Cedazo-Minguez, Angel, Björkhem, Ingemar, Wang, Yuqin, Griffiths, William J., Arenas, Ernest
Veröffentlicht in J Biol Chem (2019)

Identification of unusual oxysterols and bile acids with 7-oxo or 3β,5α,6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage fragmentation

von Griffiths, William J., Gilmore, Ian, Yutuc, Eylan, Abdel-Khalik, Jonas, Crick, Peter J., Hearn, Thomas, Dickson, Alison, Bigger, Brian W., Wu, Teresa Hoi-Yee, Goenka, Anu, Ghosh, Arunabha, Jones, Simon A., Wang, Yuqin
Veröffentlicht in J Lipid Res (2018)

Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders()()

von Griffiths, William J., Yutuc, Eylan, Abdel-Khalik, Jonas, Crick, Peter J., Hearn, Thomas, Dickson, Alison, Bigger, Brian W., Hoi-Yee Wu, Teresa, Goenka, Anu, Ghosh, Arunabha, Jones, Simon A., Covey, Douglas F., Ory, Daniel S., Wang, Yuqin
Veröffentlicht in Free Radic Biol Med (2019)

Sterols and Oxysterols in Plasma from Smith-Lemi-Opitz Syndrome Patients

von Griffiths, William J., Abdel-Khalik, Jonas, Crick, Peter J., Ogundare, Michael, Shackleton, Cedric H., Tuschl, Karin, Kwok, Mei Kwun, Bigger, Brian W., Morris, Andrew A., Honda, Akira, Xu, Libin, Porter, Ned A., Björkhem, Ingemar, Clayton, Peter T., Wang, Yuqin
Veröffentlicht in J Steroid Biochem Mol Biol (2016)

Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates

von Abdel-Khalik, Jonas, Hearn, Thomas, Dickson, Alison L., Crick, Peter J., Yutuc, Eylan, Austin-Muttitt, Karl, Bigger, Brian W., Morris, Andrew A., Shackleton, Cedric H., Clayton, Peter T., Iida, Takashi, Sircar, Ria, Rohatgi, Rajat, Marschall, Hanns-Ulrich, Sjövall, Jan, Björkhem, Ingemar, Mullins, Jonathan G.L., Griffiths, William J., Wang, Yuqin
Veröffentlicht in J Steroid Biochem Mol Biol (2021)