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Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma
Cytochrome P450 (CYP) 27A1 is a key enzyme in both the acidic and neutral pathways of bile acid biosynthesis accepting cholesterol and ring-hydroxylated sterols as substrates introducing a (25R)26-hydroxy and ultimately a (25R)26-acid group to the sterol side-chain. In human, mutations in the CYP27A...
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| Pubblicato in: | Biochim Biophys Acta Mol Cell Biol Lipids |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6327153/ https://ncbi.nlm.nih.gov/pubmed/30471425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.11.006 |
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