Identification of 7α,24-dihydroxy-3-oxocholest-4-en-26-oic and 7α,25-dihydroxy-3-oxocholest-4-en-26-oic acids in human cerebrospinal fluid and plasma

Dihydroxyoxocholestenoic acids are intermediates in bile acid biosynthesis. Here, using liquid chromatography – mass spectrometry, we confirm the identification of 7α,24-dihydroxy-3-oxocholest-4-en-26-oic and 7α,25-dihydroxy-3-oxocholest-4-en-26-oic acids in cerebrospinal fluid (CSF) based on compar...

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Bibliografiske detaljer
Udgivet i:Biochimie
Main Authors: Abdel-Khalik, Jonas, Crick, Peter J., Yutuc, Eylan, DeBarber, Andrea E., Duell, P. Barton, Steiner, Robert D., Laina, Ioanna, Wang, Yuqin, Griffiths, William J.
Format: Artigo
Sprog:Inglês
Udgivet: Editions Scientifiques Elsevier 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171785/
https://ncbi.nlm.nih.gov/pubmed/29960034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2018.06.020
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