Defective cholesterol metabolism in amyotrophic lateral sclerosis

As neurons die, cholesterol is released in the central nervous system (CNS); hence, this sterol and its metabolites may represent a biomarker of neurodegeneration, including in amyotrophic lateral sclerosis (ALS), in which altered cholesterol levels have been linked to prognosis. More than 40 differ...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Autores principales: Abdel-Khalik, Jonas, Yutuc, Eylan, Crick, Peter J., Gustafsson, Jan-Åke, Warner, Margaret, Roman, Gustavo, Talbot, Kevin, Gray, Elizabeth, Griffiths, William J., Turner, Martin R., Wang, Yuqin
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Patient-Oriented and Epidemiological Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234729/
https://ncbi.nlm.nih.gov/pubmed/27811233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P071639
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