Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders()()

Cholestane-3β,5α,6β-triol (3β,5α,6β-triol) is formed from cholestan-5,6-epoxide (5,6-EC) in a reaction catalysed by cholesterol epoxide hydrolase, following formation of 5,6-EC through free radical oxidation of cholesterol. 7-Oxocholesterol (7-OC) and 7β-hydroxycholesterol (7β-HC) can also be formed...

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Publicat a:Free Radic Biol Med
Autors principals: Griffiths, William J., Yutuc, Eylan, Abdel-Khalik, Jonas, Crick, Peter J., Hearn, Thomas, Dickson, Alison, Bigger, Brian W., Hoi-Yee Wu, Teresa, Goenka, Anu, Ghosh, Arunabha, Jones, Simon A., Covey, Douglas F., Ory, Daniel S., Wang, Yuqin
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863434/
https://ncbi.nlm.nih.gov/pubmed/31009661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.04.020
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