Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism

Dysregulated cholesterol metabolism is implicated in a number of neurological disorders. Many sterols, including cholesterol and its precursors and metabolites, are biologically active and important for proper brain function. However, spatial cholesterol metabolism in brain and the resulting sterol...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Yutuc, Eylan, Angelini, Roberto, Baumert, Mark, Mast, Natalia, Pikuleva, Irina, Newton, Jillian, Clench, Malcolm R., Skibinski, David O. F., Howell, Owain W., Wang, Yuqin, Griffiths, William J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084107/
https://ncbi.nlm.nih.gov/pubmed/32132201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917421117
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