Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism

Dysregulated cholesterol metabolism is implicated in a number of neurological disorders. Many sterols, including cholesterol and its precursors and metabolites, are biologically active and important for proper brain function. However, spatial cholesterol metabolism in brain and the resulting sterol...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Yutuc, Eylan, Angelini, Roberto, Baumert, Mark, Mast, Natalia, Pikuleva, Irina, Newton, Jillian, Clench, Malcolm R., Skibinski, David O. F., Howell, Owain W., Wang, Yuqin, Griffiths, William J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084107/
https://ncbi.nlm.nih.gov/pubmed/32132201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917421117
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