Mechanisms of Hippo pathway regulation

Por Meng, Zhipeng, Moroishi, Toshiro, Guan, Kun-Liang
Publicado no Genes Dev (2016)

YAP and TAZ: a nexus for Hippo signaling and beyond

Por Hansen, Carsten Gram, Moroishi, Toshiro, Guan, Kun-Liang
Publicado no Trends Cell Biol (2015)

The emerging roles of YAP and TAZ in cancer

Por Moroishi, Toshiro, Hansen, Carsten Gram, Guan, Kun-Liang
Publicado no Nat Rev Cancer (2015)

HERC2 Targets the Iron Regulator FBXL5 for Degradation and Modulates Iron Metabolism

Por Moroishi, Toshiro, Yamauchi, Takayoshi, Nishiyama, Masaaki, Nakayama, Keiichi I.
Publicado em 2014

MDM2 Mediates Nonproteolytic Polyubiquitylation of the DEAD-Box RNA Helicase DDX24

Por Yamauchi, Takayoshi, Nishiyama, Masaaki, Moroishi, Toshiro, Yumimoto, Kanae, Nakayama, Keiichi I.
Publicado em 2014

FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells

Por Yamauchi, Takayoshi, Nishiyama, Masaaki, Moroishi, Toshiro, Kawamura, Atsuki, Nakayama, Keiichi I.
Publicado no Mol Cell Biol (2017)

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells

Por Muto, Yoshiharu, Nishiyama, Masaaki, Nita, Akihiro, Moroishi, Toshiro, Nakayama, Keiichi I.
Publicado no Nat Commun (2017)

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

Por Moroishi, Toshiro, Hayashi, Tomoko, Pan, Wei-Wei, Fujita, Yu, Holt, Matthew V., Qin, Jun, Carson, Dennis A., Guan, Kun-Liang
Publicado no Cell (2016)

Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation

Por Lin, Kimberly C., Moroishi, Toshiro, Meng, Zhipeng, Jeong, Han-Sol, Plouffe, Steven W., Sekido, Yoshitaka, Han, Jiahuai, Park, Hyun Woo, Guan, Kun-Liang
Publicado no Nat Cell Biol (2017)

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

Por Moroishi, Toshiro, Park, Hyun Woo, Qin, Baodong, Chen, Qian, Meng, Zhipeng, Plouffe, Steven W., Taniguchi, Koji, Yu, Fa-Xing, Karin, Michael, Pan, Duojia, Guan, Kun-Liang
Publicado no Genes Dev (2015)

Alternative Wnt Signaling Activates YAP/TAZ

Por Park, Hyun Woo, Kim, Young Chul, Yu, Bo, Moroishi, Toshiro, Mo, Jung-Soon, Plouffe, Steven W., Meng, Zhipeng, Lin, Kimberly C., Yu, Fa-Xing, Alexander, Caroline M., Wang, Cunyu, Guan, Kun-Liang
Publicado no Cell (2015)

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

Por Meng, Zhipeng, Moroishi, Toshiro, Mottier-Pavie, Violaine, Plouffe, Steven W., Hansen, Carsten G., Hong, Audrey W., Park, Hyun Woo, Mo, Jung-Soon, Lu, Wenqi, Lu, Shicong, Flores, Fabian, Yu, Fa-Xing, Halder, Georg, Guan, Kun-Liang
Publicado no Nat Commun (2015)

YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis

Por Taniguchi, Koji, Moroishi, Toshiro, de Jong, Petrus R., Krawczyk, Michal, Grebbin, Britta Moyo, Luo, Huiyan, Xu, Rui-hua, Golob-Schwarzl, Nicole, Schweiger, Caroline, Wang, Kepeng, Di Caro, Giuseppe, Feng, Ying, Fearon, Eric R., Raz, Eyal, Kenner, Lukas, Farin, Henner F., Guan, Kun-Liang, Haybaeck, Johannes, Datz, Christian, Zhang, Kang, Karin, Michael
Publicado no Proc Natl Acad Sci U S A (2017)