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The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

Poorly immunogenic tumor cells evade host immunity and grow even in the presence of an intact immune system, but the complex mechanisms regulating tumor immunogenicity have not been elucidated. Here, we discovered an unexpected role of the Hippo pathway in suppressing anti-tumor immunity. We demonst...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Moroishi, Toshiro, Hayashi, Tomoko, Pan, Wei-Wei, Fujita, Yu, Holt, Matthew V., Qin, Jun, Carson, Dennis A., Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512418/
https://ncbi.nlm.nih.gov/pubmed/27912060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.005
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