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The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
Poorly immunogenic tumor cells evade host immunity and grow even in the presence of an intact immune system, but the complex mechanisms regulating tumor immunogenicity have not been elucidated. Here, we discovered an unexpected role of the Hippo pathway in suppressing anti-tumor immunity. We demonst...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512418/ https://ncbi.nlm.nih.gov/pubmed/27912060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.005 |
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