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The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

Poorly immunogenic tumor cells evade host immunity and grow even in the presence of an intact immune system, but the complex mechanisms regulating tumor immunogenicity have not been elucidated. Here, we discovered an unexpected role of the Hippo pathway in suppressing anti-tumor immunity. We demonst...

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Dades bibliogràfiques
Publicat a:Cell
Autors principals: Moroishi, Toshiro, Hayashi, Tomoko, Pan, Wei-Wei, Fujita, Yu, Holt, Matthew V., Qin, Jun, Carson, Dennis A., Guan, Kun-Liang
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512418/
https://ncbi.nlm.nih.gov/pubmed/27912060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.005
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