Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Por Ahdash, Zainab, Lau, Andy M., Martens, Chloe, Politis, Argyris
Publicado no J Vis Exp (2018)

Structural predictions of the functions of membrane proteins from HDX-MS

Por Lau, Andy M., Jia, Ruyu, Bradshaw, Richard T., Politis, Argyris
Publicado no Biochem Soc Trans (2020)

Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry

Por Lau, Andy M C, Ahdash, Zainab, Martens, Chloe, Politis, Argyris
Publicado no Bioinformatics (2019)

Surface Accessibility and Dynamics of Macromolecular Assemblies Probed by Covalent Labeling Mass Spectrometry and Integrative Modeling

Por Schmidt, Carla, Macpherson, Jamie A., Lau, Andy M., Tan, Ken Wei, Fraternali, Franca, Politis, Argyris
Publicado no Anal Chem (2017)

Direct protein-lipid interactions shape the conformational landscape of secondary transporters

Por Martens, Chloe, Shekhar, Mrinal, Borysik, Antoni J., Lau, Andy M., Reading, Eamonn, Tajkhorshid, Emad, Booth, Paula J., Politis, Argyris
Publicado no Nat Commun (2018)

A Mass‐Spectrometry‐Based Modelling Workflow for Accurate Prediction of IgG Antibody Conformations in the Gas Phase

Por Hansen, Kjetil, Lau, Andy M., Giles, Kevin, McDonnell, James M., Struwe, Weston B., Sutton, Brian J., Politis, Argyris
Publicado no Angew Chem Int Ed Engl (2018)

Structural Lipids Enable the Formation of Functional Oligomers of the Eukaryotic Purine Symporter UapA

Por Pyle, Euan, Kalli, Antreas C., Amillis, Sotiris, Hall, Zoe, Lau, Andy M., Hanyaloglu, Aylin C., Diallinas, George, Byrne, Bernadette, Politis, Argyris
Publicado no Cell Chem Biol (2018)

Mechanistic insight into the assembly of the HerA–NurA helicase–nuclease DNA end resection complex

Por Ahdash, Zainab, Lau, Andy M., Byrne, Robert Thomas, Lammens, Katja, Stüetzer, Alexandra, Urlaub, Henning, Booth, Paula J., Reading, Eamonn, Hopfner, Karl-Peter, Politis, Argyris
Publicado no Nucleic Acids Res (2017)

Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome

Por Faull, Sarah V., Lau, Andy M. C., Martens, Chloe, Ahdash, Zainab, Hansen, Kjetil, Yebenes, Hugo, Schmidt, Carla, Beuron, Fabienne, Cronin, Nora B., Morris, Edward P., Politis, Argyris
Publicado no Nat Commun (2019)

Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter

Por Jia, Ruyu, Martens, Chloe, Shekhar, Mrinal, Pant, Shashank, Pellowe, Grant A., Lau, Andy M., Findlay, Heather E., Harris, Nicola J., Tajkhorshid, Emad, Booth, Paula J., Politis, Argyris
Publicado no Nat Commun (2020)

Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry

Por Stützer, Alexandra, Welp, Luisa M., Raabe, Monika, Sachsenberg, Timo, Kappert, Christin, Wulf, Alexander, Lau, Andy M., David, Stefan-Sebastian, Chernev, Aleksandar, Kramer, Katharina, Politis, Argyris, Kohlbacher, Oliver, Fischle, Wolfgang, Urlaub, Henning
Publicado no Nat Commun (2020)

Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB

Por Reading, Eamonn, Ahdash, Zainab, Fais, Chiara, Ricci, Vito, Wang-Kan, Xuan, Grimsey, Elizabeth, Stone, Jack, Malloci, Giuliano, Lau, Andy M., Findlay, Heather, Konijnenberg, Albert, Booth, Paula J., Ruggerone, Paolo, Vargiu, Attilio V., Piddock, Laura J. V., Politis, Argyris
Publicado no Nat Commun (2020)