Revisiting the Modularity of Modular Polyketide Synthases

Por Khosla, Chaitan, Kapur, Shiven, Cane, David E.
Publicado em 2009

Role of a Conserved Arginine Residue in Linkers between the Ketosynthase and Acyltransferase Domains of Multimodular Polyketide Synthases

Por Yuzawa, Satoshi, Kapur, Shiven, Cane, David E., Khosla, Chaitan
Publicado em 2012

Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase

Por Kapur, Shiven, Chen, Alice Y., Cane, David E., Khosla, Chaitan
Publicado em 2010

Mechanism based protein cross-linking of domains from the 6-deoxyerythronolide B synthase

Por Kapur, Shiven, Worthington, Andrew, Tang, Yinyan, Cane, David E., Burkart, Michael D., Khosla, Chaitan
Publicado em 2008

Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation

Por Kapur, Shiven, Lowry, Brian, Yuzawa, Satoshi, Kenthirapalan, Sanketha, Chen, Alice Y., Cane, David E., Khosla, Chaitan
Publicado em 2012

Engineered ligand‐based VEGFR antagonists with increased receptor binding affinity more effectively inhibit angiogenesis

Por Kapur, Shiven, Silverman, Adam P., Ye, Anne Z., Papo, Niv, Jindal, Darren, Blumenkranz, Mark S., Cochran, Jennifer R.
Publicado no Bioeng Transl Med (2017)

An engineered Axl ‘decoy receptor’ effectively silences the Gas6/Axl signaling axis

Por Kariolis, Mihalis S., Miao, Yu Rebecca, Jones, Douglas S., Kapur, Shiven, Mathews, Irimpan I., Giaccia, Amato J., Cochran, Jennifer R.
Publicado no Nat Chem Biol (2014)

Probing the interactions of an acyl carrier protein domain from the 6-deoxyerythronolide B synthase

Por Charkoudian, Louise K, Liu, Corey W, Capone, Stefania, Kapur, Shiven, Cane, David E, Togni, Antonio, Seebach, Dieter, Khosla, Chaitan
Publicado em 2011

Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies

Por Kariolis, Mihalis S., Miao, Yu Rebecca, Diep, Anh, Nash, Shannon E., Olcina, Monica M., Jiang, Dadi, Jones, Douglas S., Kapur, Shiven, Mathews, Irimpan I., Koong, Albert C., Rankin, Erinn B., Cochran, Jennifer R., Giaccia, Amato J.
Publicado no J Clin Invest (2016)