YKL-40 in Pediatric Asthma, MUC5B Promoter Polymorphism in Idiopathic Pulmonary Fibrosis, and Esmolol in Septic Shock

Por Kulkarni, Hrishikesh S., Guzy, Robert D., McEvoy, Colleen
Publicado no Am J Respir Crit Care Med (2014)

Loss of the SdhB, but Not the SdhA, Subunit of Complex II Triggers Reactive Oxygen Species-Dependent Hypoxia-Inducible Factor Activation and Tumorigenesis

Por Guzy, Robert D., Sharma, Bhumika, Bell, Eric, Chandel, Navdeep S., Schumacker, Paul T.
Publicado em 2008

Fibroblast Growth Factor 2 Is Required for Epithelial Recovery, but Not for Pulmonary Fibrosis, in Response to Bleomycin

Por Guzy, Robert D., Stoilov, Ivan, Elton, Timothy J., Mecham, Robert P., Ornitz, David M.
Publicado no Am J Respir Cell Mol Biol (2015)

FGFR2 Is Required for AEC2 Homeostasis and Survival after Bleomycin-induced Lung Injury

Por Dorry, Samuel J., Ansbro, Brandon O., Ornitz, David M., Mutlu, Gökhan M., Guzy, Robert D.
Publicado no Am J Respir Cell Mol Biol (2020)

Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling

Por Guzy, Robert D., Li, Ling, Smith, Craig, Dorry, Samuel J., Koo, Hyun Young, Chen, Lin, Ornitz, David M.
Publicado no J Biol Chem (2017)

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation

Por Mansfield, Kyle D., Guzy, Robert D., Pan, Yi, Young, Regina M., Cash, Timothy P., Schumacker, Paul T., Simon, M. Celeste
Publicado em 2005

MITOCHONDRIAL OXIDANT STRESS TRIGGERS CELL DEATH IN SIMULATED ISCHEMIA-REPERFUSION

Por Loor, Gabriel, Kondapalli, Jyothisri, Iwase, Hirotaro, Chandel, Navdeep S., Waypa, Gregory B., Guzy, Robert D., Hoek, Terry L. Vanden, Schumacker, Paul T.
Publicado em 2010

Sustained Smad2 Phosphorylation Is Required for Myofibroblast Transformation in Response to TGF-β

Por Ard, Shawn, Reed, Eleanor B., Smolyaninova, Larisa V., Orlov, Sergei N., Mutlu, Gökhan M., Guzy, Robert D., Dulin, Nickolai O.
Publicado no Am J Respir Cell Mol Biol (2019)

Superoxide Generated at Mitochondrial Complex III Triggers Acute Responses to Hypoxia in the Pulmonary Circulation

Por Waypa, Gregory B., Marks, Jeremy D., Guzy, Robert D., Mungai, Paul T., Schriewer, Jacqueline M., Dokic, Danijela, Ball, Molly K., Schumacker, Paul T.
Publicado em 2013

Fibroblast growth factor 2 decreases bleomycin-induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation

Por Koo, Hyun Young, El-Baz, Lamis M.F., House, Stacey L., Cilvik, Sarah N., Dorry, Samuel J., Shoukry, Nahla M., Salem, Mohamed L., Hafez, Hani S., Dulin, Nickolai O., Ornitz, David M., Guzy, Robert D.
Publicado no J Pathol (2018)

Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis

Por Hamanaka, Robert B., Nigdelioglu, Recep, Meliton, Angelo Y., Tian, Yufeng, Witt, Leah J., O’Leary, Erin, Sun, Kaitlyn A., Woods, Parker S., Wu, David, Ansbro, Brandon, Ard, Shawn, Rohde, Jason M., Dulin, Nickolai O., Guzy, Robert D., Mutlu, Gökhan M.
Publicado no Am J Respir Cell Mol Biol (2018)

Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization

Por Lee, Tzu-Han, Yeh, Chih-Fan, Lee, Ying-Tung, Shih, Ying-Chun, Chen, Yen-Ting, Hung, Chen-Ting, You, Ming-Yi, Wu, Pei-Chen, Shentu, Tzu-Pin, Huang, Ru-Ting, Lin, Yu-Shan, Wu, Yueh-Feng, Lin, Sung-Jan, Lu, Frank-Leigh, Tsao, Po-Nien, Lin, Tzu-Hung, Lo, Shen-Chuan, Tseng, Yi-Shuan, Wu, Wan-Lin, Chen, Chiung-Nien, Wu, Chau-Chung, Lin, Shuei-Liong, Sperling, Anne I., Guzy, Robert D., Fang, Yun, Yang, Kai-Chien
Publicado no Nat Commun (2020)

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

Por Reyfman, Paul A., Walter, James M., Joshi, Nikita, Anekalla, Kishore R., McQuattie-Pimentel, Alexandra C., Chiu, Stephen, Fernandez, Ramiro, Akbarpour, Mahzad, Chen, Ching-I, Ren, Ziyou, Verma, Rohan, Abdala-Valencia, Hiam, Nam, Kiwon, Chi, Monica, Han, SeungHye, Gonzalez-Gonzalez, Francisco J., Soberanes, Saul, Watanabe, Satoshi, Williams, Kinola J. N., Flozak, Annette S., Nicholson, Trevor T., Morgan, Vince K., Winter, Deborah R., Hinchcliff, Monique, Hrusch, Cara L., Guzy, Robert D., Bonham, Catherine A., Sperling, Anne I., Bag, Remzi, Hamanaka, Robert B., Mutlu, Gökhan M., Yeldandi, Anjana V., Marshall, Stacy A., Shilatifard, Ali, Amaral, Luis A. N., Perlman, Harris, Sznajder, Jacob I., Argento, A. Christine, Gillespie, Colin T., Dematte, Jane, Jain, Manu, Singer, Benjamin D., Ridge, Karen M., Lam, Anna P., Bharat, Ankit, Bhorade, Sangeeta M., Gottardi, Cara J., Budinger, G. R. Scott, Misharin, Alexander V.
Publicado no Am J Respir Crit Care Med (2019)