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Fibroblast growth factor 2 decreases bleomycin-induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation

Fibroblast growth factor (FGF) signaling has been implicated in the pathogenesis of pulmonary fibrosis. Mice lacking FGF2 have increased mortality and impaired epithelial recovery after bleomycin exposure, supporting a protective or reparative function following lung injury. To determine whether FGF...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Koo, Hyun Young, El-Baz, Lamis M.F., House, Stacey L., Cilvik, Sarah N., Dorry, Samuel J., Shoukry, Nahla M., Salem, Mohamed L., Hafez, Hani S., Dulin, Nickolai O., Ornitz, David M., Guzy, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175645/
https://ncbi.nlm.nih.gov/pubmed/29873400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5106
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