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FGFR2 Is Required for AEC2 Homeostasis and Survival after Bleomycin-induced Lung Injury

Alveolar epithelial cell (AEC) injury is central to the pathogenesis of pulmonary fibrosis. Epithelial FGF (fibroblast growth factor) signaling is essential for recovery from hyperoxia- and influenza-induced lung injury, and treatment with FGFs is protective in experimental lung injury. The cell typ...

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Библиографические подробности
Опубликовано в: :Am J Respir Cell Mol Biol
Главные авторы: Dorry, Samuel J., Ansbro, Brandon O., Ornitz, David M., Mutlu, Gökhan M., Guzy, Robert D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193788/
https://ncbi.nlm.nih.gov/pubmed/31860803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0079OC
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