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Fibroblast Growth Factor 2 Is Required for Epithelial Recovery, but Not for Pulmonary Fibrosis, in Response to Bleomycin

The pathogenesis of pulmonary fibrosis involves lung epithelial injury and aberrant proliferation of fibroblasts, and results in progressive pulmonary scarring and declining lung function. In vitro, fibroblast growth factor (FGF) 2 promotes myofibroblast differentiation and proliferation in cooperat...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Guzy, Robert D., Stoilov, Ivan, Elton, Timothy J., Mecham, Robert P., Ornitz, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370255/
https://ncbi.nlm.nih.gov/pubmed/24988442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0184OC
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