Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation

Aberrant activation of TGF-β1 is frequently encountered and promotes epithelial-mesenchymal transition (EMT) and fibroblast activation in pulmonary fibrosis. The present study investigated whether emodin mediates its effect via suppressing TGF-β1-induced EMT and fibroblast activation in bleomycin (B...

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Publicado no:Sci Rep
Main Authors: Guan, Ruijuan, Wang, Xia, Zhao, Xiaomei, Song, Nana, Zhu, Jimin, Wang, Jijiang, Wang, Jin, Xia, Chunmei, Chen, Yonghua, Zhu, Danian, Shen, Linlin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075925/
https://ncbi.nlm.nih.gov/pubmed/27774992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35696
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