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Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial–mesenchymal transition and fibroblast activation

Idiopathic pulmonary fibrosis (IPF) is a serious progressive and irreversible lung disease with unknown etiology and few treatment options. This disease was once thought to be a chronic inflammatory-driven process, but it is increasingly recognized that the epithelial–mesenchymal transition (EMT) co...

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Detalhes bibliográficos
Main Authors: Chen, Y-L, Zhang, X, Bai, J, Gai, L, Ye, X-L, Zhang, L, Xu, Q, Zhang, Y-X, Xu, L, Li, H-P, Ding, X
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698540/
https://ncbi.nlm.nih.gov/pubmed/23764846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.154
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