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Fibroblast Growth Factor 2 Is Required for Epithelial Recovery, but Not for Pulmonary Fibrosis, in Response to Bleomycin

The pathogenesis of pulmonary fibrosis involves lung epithelial injury and aberrant proliferation of fibroblasts, and results in progressive pulmonary scarring and declining lung function. In vitro, fibroblast growth factor (FGF) 2 promotes myofibroblast differentiation and proliferation in cooperat...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Guzy, Robert D., Stoilov, Ivan, Elton, Timothy J., Mecham, Robert P., Ornitz, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370255/
https://ncbi.nlm.nih.gov/pubmed/24988442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0184OC
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